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Actin Microfilament Mediates Osteoblast Cbfa1 Responsiveness to BMP2 under Simulated Microgravity
Microgravity decreases osteoblastic activity, induces actin microfilament disruption and inhibits the responsiveness of osteoblast to cytokines, but the mechanisms remains enigmatic. The F-actin cytoskeleton has previously been implicated in manifold changes of cell shape, function and signaling obs...
Autores principales: | Dai, Zhongquan, Wu, Feng, Chen, Jian, Xu, Hongjie, Wang, Honghui, Guo, Feima, Tan, Yingjun, Ding, Bai, Wang, Jinfu, Wan, Yumin, Li, Yinghui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651164/ https://www.ncbi.nlm.nih.gov/pubmed/23675497 http://dx.doi.org/10.1371/journal.pone.0063661 |
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