Pin1 Null Mice Exhibit Low Bone Mass and Attenuation of BMP Signaling

Bone is constantly formed and resorbed throughout life by coordinated actions of osteoblasts and osteoclasts. However, the molecular mechanisms involved in osteoblast function remain incompletely understood. Here we show, for the first time, that the peptidyl-prolyl isomerase PIN1 controls the osteo...

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Detalles Bibliográficos
Autores principales: Shen, Zhong-Jian, Hu, Jie, Ali, Aktar, Pastor, Johanne, Shiizaki, Kazuhiro, Blank, Robert D., Kuro-o, Makoto, Malter, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651169/
https://www.ncbi.nlm.nih.gov/pubmed/23675491
http://dx.doi.org/10.1371/journal.pone.0063565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651169/
https://www.ncbi.nlm.nih.gov/pubmed/23675491
http://dx.doi.org/10.1371/journal.pone.0063565

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