Hypoxic Tumor Kinase Signaling Mediated by STAT5A in Development of Castration-Resistant Prostate Cancer

In this study, we hypothesized that androgen-deprivation therapy (ADT) in prostate cancer, although initially efficient, induces changes in the tumor kinome, which subsequently promote development of castration-resistant (CR) disease. Recognizing the correlation between tumor hypoxia and poor progno...

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Detalles Bibliográficos
Autores principales: Røe, Kathrine, Bratland, Åse, Vlatkovic, Ljiljana, Ragnum, Harald Bull, Saelen, Marie Grøn, Olsen, Dag Rune, Marignol, Laure, Ree, Anne Hansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651196/
https://www.ncbi.nlm.nih.gov/pubmed/23675504
http://dx.doi.org/10.1371/journal.pone.0063723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651196/
https://www.ncbi.nlm.nih.gov/pubmed/23675504
http://dx.doi.org/10.1371/journal.pone.0063723

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