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Hypoxic Tumor Kinase Signaling Mediated by STAT5A in Development of Castration-Resistant Prostate Cancer
In this study, we hypothesized that androgen-deprivation therapy (ADT) in prostate cancer, although initially efficient, induces changes in the tumor kinome, which subsequently promote development of castration-resistant (CR) disease. Recognizing the correlation between tumor hypoxia and poor progno...
Autores principales: | Røe, Kathrine, Bratland, Åse, Vlatkovic, Ljiljana, Ragnum, Harald Bull, Saelen, Marie Grøn, Olsen, Dag Rune, Marignol, Laure, Ree, Anne Hansen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651196/ https://www.ncbi.nlm.nih.gov/pubmed/23675504 http://dx.doi.org/10.1371/journal.pone.0063723 |
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