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Upregulation of miR-150* and miR-630 Induces Apoptosis in Pancreatic Cancer Cells by Targeting IGF-1R

MicroRNAs have been implicated in many critical cellular processes including apoptosis. We have previously found that apoptosis in pancreatic cancer cells was induced by adamantyl retinoid-related (ARR) molecule 3-Cl-AHPC. Here we report that 3-Cl-AHPC-dependent apoptosis involves regulating a numbe...

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Detalles Bibliográficos
Autores principales: Farhana, Lulu, Dawson, Marcia I., Murshed, Farhan, Das, Jayanta K., Rishi, Arun K., Fontana, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651232/
https://www.ncbi.nlm.nih.gov/pubmed/23675407
http://dx.doi.org/10.1371/journal.pone.0061015