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Optimal precursor ion selection for LC-MALDI MS/MS

BACKGROUND: Liquid chromatography mass spectrometry (LC-MS) maps in shotgun proteomics are often too complex to select every detected peptide signal for fragmentation by tandem mass spectrometry (MS/MS). Standard methods for precursor ion selection, commonly based on data dependent acquisition, sele...

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Detalles Bibliográficos
Autores principales: Zerck, Alexandra, Nordhoff, Eckhard, Lehrach, Hans, Reinert, Knut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651328/
https://www.ncbi.nlm.nih.gov/pubmed/23418672
http://dx.doi.org/10.1186/1471-2105-14-56