Accumulation profiles of PrP(Sc) in hemal nodes of naturally and experimentally scrapie-infected sheep

BACKGROUND: In classical scrapie, the disease-associated abnormal isoform (PrP(Sc)) of normal prion protein accumulates principally in the nervous system and lymphoid tissues of small ruminants. Lymph nodes traffic leukocytes via lymphatic and blood vasculatures but hemal nodes lack lymphatic vessel...

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Detalles Bibliográficos
Autores principales: Dassanayake, Rohana P, Truscott, Thomas C, Özyiğit, M Özgür, Zhuang, Dongyue, Schneider, David A, O’Rourke, Katherine I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651361/
https://www.ncbi.nlm.nih.gov/pubmed/23601183
http://dx.doi.org/10.1186/1746-6148-9-82

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651361/
https://www.ncbi.nlm.nih.gov/pubmed/23601183
http://dx.doi.org/10.1186/1746-6148-9-82

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