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Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity

BACKGROUND: Multiple Sclerosis (MS) is considered a T-cell-mediated autoimmune disease with a prototypical oscillatory behavior, as evidenced by the presence of clinical relapses. Understanding the dynamics of immune cells governing the course of MS, therefore, has many implications for immunotherap...

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Detalles Bibliográficos
Autores principales: Martinez-Pasamar, Sara, Abad, Elena, Moreno, Beatriz, Velez de Mendizabal, Nieves, Martinez-Forero, Ivan, Garcia-Ojalvo, Jordi, Villoslada, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651362/
https://www.ncbi.nlm.nih.gov/pubmed/23618467
http://dx.doi.org/10.1186/1752-0509-7-34