Functional analysis of the impact of ORMDL3 expression on inflammation and activation of the unfolded protein response in human airway epithelial cells

BACKGROUND: The gene ORMDL3 was shown to be associated with early-onset asthma susceptibility in multiple independent genome-wide and candidate-gene association studies. Asthmatic patients have elevated expression levels of this gene. ORMDL3 encodes a transmembrane protein localized in the endoplasm...

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Detalles Bibliográficos
Autores principales: Hsu, Karolynn J, Turvey, Stuart E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651386/
https://www.ncbi.nlm.nih.gov/pubmed/23369242
http://dx.doi.org/10.1186/1710-1492-9-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651386/
https://www.ncbi.nlm.nih.gov/pubmed/23369242
http://dx.doi.org/10.1186/1710-1492-9-4

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