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Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

BACKGROUND: The proteoglycan biglycan (BGN) is involved in collagen fibril assembly and its fragmentation is likely to be associated with collagen turnover during the pathogenesis of diseases which involve dysregulated extracellular matrix remodeling (ECMR), such as rheumatoid arthritis (RA) and liv...

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Detalles Bibliográficos
Autores principales: Genovese, Federica, Barascuk, Natasha, Larsen, Lise, Larsen, Martin Røssel, Nawrocki, Arkadiusz, Li, Yili, Zheng, Qinlong, Wang, Jianxia, Veidal, Sanne Skovgård, Leeming, Diana Julie, Karsdal, Morten Asser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651402/
https://www.ncbi.nlm.nih.gov/pubmed/23635022
http://dx.doi.org/10.1186/1755-1536-6-9