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Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases
BACKGROUND: The proteoglycan biglycan (BGN) is involved in collagen fibril assembly and its fragmentation is likely to be associated with collagen turnover during the pathogenesis of diseases which involve dysregulated extracellular matrix remodeling (ECMR), such as rheumatoid arthritis (RA) and liv...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651402/ https://www.ncbi.nlm.nih.gov/pubmed/23635022 http://dx.doi.org/10.1186/1755-1536-6-9 |