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Cancer: a “stem-cell” disease?

BACKGROUND: Nowadays, we believe that cancer is a genetic disease. We focus on the genetic targets and epigenetic changes in a tumor. Remarkably, many crucial signal pathways in a malignant cell involve “stem-ness” genes. The prevalence of stem-ness in cancer suggests that cancer has a stem-cell ori...

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Detalles Bibliográficos
Autor principal: Tu, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651409/
https://www.ncbi.nlm.nih.gov/pubmed/23647946
http://dx.doi.org/10.1186/1475-2867-13-40