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Cancer: a “stem-cell” disease?
BACKGROUND: Nowadays, we believe that cancer is a genetic disease. We focus on the genetic targets and epigenetic changes in a tumor. Remarkably, many crucial signal pathways in a malignant cell involve “stem-ness” genes. The prevalence of stem-ness in cancer suggests that cancer has a stem-cell ori...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651409/ https://www.ncbi.nlm.nih.gov/pubmed/23647946 http://dx.doi.org/10.1186/1475-2867-13-40 |