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An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells

Lipodystrophies, characterized by partial or complete loss of adipose tissue, have been associated with mutations in the lamin A gene. It remains unclear how lamin A mutants interfere with adipose tissue formation. Hutchinson–Gilford progeria syndrome (HGPS) presents the most severe form of lamin A-...

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Detalles Bibliográficos
Autores principales: Xiong, Zheng-Mei, LaDana, Christina, Wu, Di, Cao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651521/
https://www.ncbi.nlm.nih.gov/pubmed/23596277