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An inhibitory role of progerin in the gene induction network of adipocyte differentiation from iPS cells
Lipodystrophies, characterized by partial or complete loss of adipose tissue, have been associated with mutations in the lamin A gene. It remains unclear how lamin A mutants interfere with adipose tissue formation. Hutchinson–Gilford progeria syndrome (HGPS) presents the most severe form of lamin A-...
Autores principales: | Xiong, Zheng-Mei, LaDana, Christina, Wu, Di, Cao, Kan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651521/ https://www.ncbi.nlm.nih.gov/pubmed/23596277 |
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