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Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila
Sir2 is the most intensively discussed longevity gene in current aging research. Although, the gene encoding for a NAD(+)-dependent histone deacetylase initially was found to extend lifespan of various organisms ranging from yeast to mammals, serious doubts regarding its role in longevity have been...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651523/ https://www.ncbi.nlm.nih.gov/pubmed/23765091 |