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Controlled delivery of bioactive molecules into live cells using the bacterial mechanosensitive channel MscL
Bacterial mechanosensitive channels are some of the largest pores in nature. In particular, MscL, with a pore diameter > 25 Å, allows passage of large organic ions and small proteins. Functional MscL reconstitution into lipids has been proposed for applications in vesicular-based drug release. He...
Autores principales: | Doerner, Julia F., Febvay, Sebastien, Clapham, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651673/ https://www.ncbi.nlm.nih.gov/pubmed/22871809 http://dx.doi.org/10.1038/ncomms1999 |
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