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Determination of the optimal tubulin isotype target as a method for the development of individualized cancer chemotherapy
BACKGROUND: As microtubules are essential for cell growth and division, its constituent protein β-tubulin has been a popular target for various treatments, including cancer chemotherapy. There are several isotypes of human β-tubulin and each type of cell expresses its characteristic distribution of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651705/ https://www.ncbi.nlm.nih.gov/pubmed/23634782 http://dx.doi.org/10.1186/1742-4682-10-29 |