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Determination of the optimal tubulin isotype target as a method for the development of individualized cancer chemotherapy

BACKGROUND: As microtubules are essential for cell growth and division, its constituent protein β-tubulin has been a popular target for various treatments, including cancer chemotherapy. There are several isotypes of human β-tubulin and each type of cell expresses its characteristic distribution of...

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Detalles Bibliográficos
Autores principales:	Ravanbakhsh, Siamak, Gajewski, Melissa, Greiner, Russell, Tuszynski, Jack A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651705/ https://www.ncbi.nlm.nih.gov/pubmed/23634782 http://dx.doi.org/10.1186/1742-4682-10-29

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