DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair

Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are two distinct DNA double-strand break (DSB) repair pathways. Here we report that DNA-dependent protein kinase (DNA-PK), the core component of NHEJ, partnering with DNA-damage checkpoint kinases ataxia telangiectasia mutated (ATM)...

Descripción completa

Detalles Bibliográficos
Autores principales: Serrano, Moises A., Li, Zhengke, Dangeti, Mohan, Musich, Phillip R., Patrick, Steve, Roginskaya, Marina, Cartwright, Brian, Zou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651755/
https://www.ncbi.nlm.nih.gov/pubmed/22797063
http://dx.doi.org/10.1038/onc.2012.257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651755/
https://www.ncbi.nlm.nih.gov/pubmed/22797063
http://dx.doi.org/10.1038/onc.2012.257

Ejemplares similares