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Warfarin dose prediction in children using pharmacometric bridging—comparison with published pharmacogenetic dosing algorithms
PURPOSE: Numerous studies have investigated causes of warfarin dose variability in adults, whereas studies in children are limited both in numbers and size. Mechanism-based population modelling provides an opportunity to condense and propagate prior knowledge from one population to another. The main...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651819/ https://www.ncbi.nlm.nih.gov/pubmed/23307232 http://dx.doi.org/10.1007/s00228-012-1466-4 |