Cargando…

Warfarin dose prediction in children using pharmacometric bridging—comparison with published pharmacogenetic dosing algorithms

PURPOSE: Numerous studies have investigated causes of warfarin dose variability in adults, whereas studies in children are limited both in numbers and size. Mechanism-based population modelling provides an opportunity to condense and propagate prior knowledge from one population to another. The main...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamberg, Anna-Karin, Friberg, Lena E., Hanséus, Katarina, Ekman-Joelsson, Britt-Marie, Sunnegårdh, Jan, Jonzon, Anders, Lundell, Bo, Jonsson, E. Niclas, Wadelius, Mia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651819/
https://www.ncbi.nlm.nih.gov/pubmed/23307232
http://dx.doi.org/10.1007/s00228-012-1466-4