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Warfarin dose prediction in children using pharmacometric bridging—comparison with published pharmacogenetic dosing algorithms

PURPOSE: Numerous studies have investigated causes of warfarin dose variability in adults, whereas studies in children are limited both in numbers and size. Mechanism-based population modelling provides an opportunity to condense and propagate prior knowledge from one population to another. The main...

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Detalles Bibliográficos
Autores principales:	Hamberg, Anna-Karin, Friberg, Lena E., Hanséus, Katarina, Ekman-Joelsson, Britt-Marie, Sunnegårdh, Jan, Jonzon, Anders, Lundell, Bo, Jonsson, E. Niclas, Wadelius, Mia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Pharmacogenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651819/ https://www.ncbi.nlm.nih.gov/pubmed/23307232 http://dx.doi.org/10.1007/s00228-012-1466-4

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