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Current perspectives on the intensity of natural selection of MHC loci
Polymorphism of genes in the major histocompatibility complex (MHC) is believed to be maintained by balancing selection. However, direct evidence of selection has proven difficult to demonstrate. In 1994, Satta and colleagues estimated the selection intensity of the human MHC (human leukocyte antige...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer-Verlag
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651823/ https://www.ncbi.nlm.nih.gov/pubmed/23549729 http://dx.doi.org/10.1007/s00251-013-0693-x |