Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids

Fibroblast growth factor 19 (FGF19) is proposed to be a negative feedback regulator of hepatic bile acid (BA) synthesis. We aimed to clarify the distribution of FGF19 expression in human intestine and to investigate induction in a novel explant system. Ileal and colonic mucosal biopsies were obtaine...

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Detalles Bibliográficos
Autores principales: Zhang, Justine H., Nolan, Jonathan D., Kennie, Sarah L., Johnston, Ian M., Dew, Tracy, Dixon, Peter H., Williamson, Catherine, Walters, Julian R. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2013
Materias:
Hormones and Signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652069/
https://www.ncbi.nlm.nih.gov/pubmed/23518683
http://dx.doi.org/10.1152/ajpgi.00398.2012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652069/
https://www.ncbi.nlm.nih.gov/pubmed/23518683
http://dx.doi.org/10.1152/ajpgi.00398.2012

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