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Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids
Fibroblast growth factor 19 (FGF19) is proposed to be a negative feedback regulator of hepatic bile acid (BA) synthesis. We aimed to clarify the distribution of FGF19 expression in human intestine and to investigate induction in a novel explant system. Ileal and colonic mucosal biopsies were obtaine...
Autores principales: | Zhang, Justine H., Nolan, Jonathan D., Kennie, Sarah L., Johnston, Ian M., Dew, Tracy, Dixon, Peter H., Williamson, Catherine, Walters, Julian R. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652069/ https://www.ncbi.nlm.nih.gov/pubmed/23518683 http://dx.doi.org/10.1152/ajpgi.00398.2012 |
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