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Aging decreases antioxidant effects and increases lipid peroxidation in the Apolipoprotein E deficient mouse

In this study, to study the effect of aging and Apolipoprotein E (ApoE) deficiency on antioxidant ability in mice, we examined whether lipid peroxidation is promoted by aging in ApoE deficient (ApoE(−/−)) mice, which have a shorter lifespan than normal mice. The levels of thiobarbituric acid-reactiv...

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Detalles Bibliográficos
Autores principales: Honma, Taro, Tsuduki, Tsuyoshi, Sugawara, Soko, Kitano, Yasuna, Ito, Junya, Kijima, Ryo, Tsubata, Mari, Nakagawa, Kiyotaka, Miyazawa, Teruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652298/
https://www.ncbi.nlm.nih.gov/pubmed/23704813
http://dx.doi.org/10.3164/jcbn.12-85