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Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing

The competition between viruses and hosts is played out in all branches of life. Many prokaryotes have an adaptive immune system termed ‘CRISPR’ (clustered regularly interspaced short palindromic repeats) which is based on the capture of short pieces of viral DNA. The captured DNA is integrated into...

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Detalles Bibliográficos
Autores principales: Reeks, Judith, Sokolowski, Richard D., Graham, Shirley, Liu, Huanting, Naismith, James H., White, Malcolm F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652601/
https://www.ncbi.nlm.nih.gov/pubmed/23527601
http://dx.doi.org/10.1042/BJ20130269