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The role of the cerebral capillaries in acute ischemic stroke: the extended penumbra model

The pathophysiology of cerebral ischemia is traditionally understood in relation to reductions in cerebral blood flow (CBF). However, a recent reanalysis of the flow-diffusion equation shows that increased capillary transit time heterogeneity (CTTH) can reduce the oxygen extraction efficacy in brain...

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Detalles Bibliográficos
Autores principales: Østergaard, Leif, Jespersen, Sune Nørhøj, Mouridsen, Kim, Mikkelsen, Irene Klærke, Jonsdottír, Kristjana Ýr, Tietze, Anna, Blicher, Jakob Udby, Aamand, Rasmus, Hjort, Niels, Iversen, Nina Kerting, Cai, Changsi, Hougaard, Kristina Dupont, Simonsen, Claus Z, Von Weitzel-Mudersbach, Paul, Modrau, Boris, Nagenthiraja, Kartheeban, Riisgaard Ribe, Lars, Hansen, Mikkel Bo, Bekke, Susanne Lise, Dahlman, Martin Gervais, Puig, Josep, Pedraza, Salvador, Serena, Joaquín, Cho, Tae-Hee, Siemonsen, Susanne, Thomalla, Götz, Fiehler, Jens, Nighoghossian, Norbert, Andersen, Grethe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652700/
https://www.ncbi.nlm.nih.gov/pubmed/23443173
http://dx.doi.org/10.1038/jcbfm.2013.18