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Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABA(A) receptors

BACKGROUND: GABAergic deficit is one of the major mechanisms underlying epileptic seizures. Previous studies have mainly focused on alterations of synaptic GABAergic inhibition during epileptogenesis. Recent work suggested that tonic inhibition may also play a role in regulating epileptogenesis, but...

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Detalles Bibliográficos
Autores principales: Sun, Yajie, Wu, Zheng, Kong, Shuzhen, Jiang, Dongyun, Pitre, Anar, Wang, Yun, Chen, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652748/
https://www.ncbi.nlm.nih.gov/pubmed/23634821
http://dx.doi.org/10.1186/1756-6606-6-21