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Investigating the relationship between predictability and imbalance in minimisation: a simulation study

BACKGROUND: The use of restricted randomisation methods such as minimisation is increasing. This paper investigates under what conditions it is preferable to use restricted randomisation in order to achieve balance between treatment groups at baseline with regard to important prognostic factors and...

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Detalles Bibliográficos
Autores principales: McPherson, Gladys C, Campbell, Marion K, Elbourne, Diana R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652769/
https://www.ncbi.nlm.nih.gov/pubmed/23537389
http://dx.doi.org/10.1186/1745-6215-14-86