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Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration

BACKGROUND: The directional migration and the following development of primordial germ cells (PGCs) during gonad formation are key steps for germline development. It has been proposed that the interaction between germ cells and genital ridge (GR) somatic cells plays essential roles in this process....

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Detalles Bibliográficos
Autores principales: Chen, Su-Ren, Zheng, Qiao-Song, Zhang, Yang, Gao, Fei, Liu, Yi-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652777/
https://www.ncbi.nlm.nih.gov/pubmed/23497137
http://dx.doi.org/10.1186/1741-7007-11-22