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Frequency of intron loss correlates with processed pseudogene abundance: a novel strategy to test the reverse transcriptase model of intron loss

BACKGROUND: Although intron loss in evolution has been described, the mechanism involved is still unclear. Three models have been proposed, the reverse transcriptase (RT) model, genomic deletion model and double-strand-break repair model. The RT model, also termed mRNA-mediated intron loss, suggests...

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Detalles Bibliográficos
Autores principales: Zhu, Tao, Niu, Deng-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652778/
https://www.ncbi.nlm.nih.gov/pubmed/23497167
http://dx.doi.org/10.1186/1741-7007-11-23