Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity

BACKGROUND: N-methyl-D-aspartate receptors (NMDARs) are critical for neuronal development and synaptic plasticity. Dysregulation of NMDARs is implicated in neuropsychiatric disorders. Native NMDARs are heteromultimeric protein complexes consisting of NR1 and NR2 subunits. NR2 subunits (NR2A–D) are t...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Ning, Hayashi, Hideki, Aida, Tomomi, Namekata, Kazuhiko, Harada, Takayuki, Mishina, Masayoshi, Tanaka, Kohichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652797/
https://www.ncbi.nlm.nih.gov/pubmed/23641686
http://dx.doi.org/10.1186/1756-6606-6-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652797/
https://www.ncbi.nlm.nih.gov/pubmed/23641686
http://dx.doi.org/10.1186/1756-6606-6-22

Ejemplares similares