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Thymidylate Synthase Expression Determines Pemetrexed Targets and Resistance Development in Tumour Cells

Although treatment options for cancer patients are increasing every year, the drug resistance problem remains very present. It is very difficult to find a drug that acts equally on tumours of the same histology as the individual's genetic characteristics often determine the response to treatmen...

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Detalles Bibliográficos
Autores principales: Buqué, Aitziber, Aresti, Unai, Calvo, Begoña, Sh. Muhialdin, Jangi, Muñoz, Alberto, Carrera, Sergio, Azkona, Eider, Rubio, Itziar, López-Vivanco, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652812/
https://www.ncbi.nlm.nih.gov/pubmed/23675481
http://dx.doi.org/10.1371/journal.pone.0063338