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Thymidylate Synthase Expression Determines Pemetrexed Targets and Resistance Development in Tumour Cells
Although treatment options for cancer patients are increasing every year, the drug resistance problem remains very present. It is very difficult to find a drug that acts equally on tumours of the same histology as the individual's genetic characteristics often determine the response to treatmen...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652812/ https://www.ncbi.nlm.nih.gov/pubmed/23675481 http://dx.doi.org/10.1371/journal.pone.0063338 |