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Antithrombin Regulates Matriptase Activity Involved in Plasmin Generation, Syndecan Shedding, and HGF Activation in Keratinocytes

Matriptase, a membrane-associated serine protease, plays an essential role in epidermal barrier function through activation of the glycosylphosphatidylinositol (GPI)-anchored serine protease prostasin. The matriptase-prostasin proteolytic cascade is tightly regulated by hepatocyte growth factor acti...

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Detalles Bibliográficos
Autores principales: Chen, Ya-Wen, Xu, Zhenghong, Baksh, Adrienne N. H., Wang, Jehng-Kang, Chen, Chiu-Yuan, Swanson, Richard, Olson, Steve T., Kataoka, Hiroaki, Johnson, Michael D., Lin, Chen-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652837/
https://www.ncbi.nlm.nih.gov/pubmed/23675430
http://dx.doi.org/10.1371/journal.pone.0062826