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Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, a...

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Detalles Bibliográficos
Autores principales: Minato, Yusuke, Fassio, Sara R., Häse, Claudia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652848/
https://www.ncbi.nlm.nih.gov/pubmed/23675480
http://dx.doi.org/10.1371/journal.pone.0063336