The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011

Single Nucleotide Polymorphisms (SNPs) in the Pfmdr1, and Pfcrt, genes of Plasmodium falciparum may confer resistance to a number of anti-malaria drugs. Pfmdr1 86Y and haplotypes at Pfcrt 72-76 have been linked to chloroquine (CQ) as well as amodiaquine (AQ) resistance. mefloquine (MQ) and lumefantr...

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Detalles Bibliográficos
Autores principales: Eyase, Fredrick L., Akala, Hoseah M., Ingasia, Luiser, Cheruiyot, Agnes, Omondi, Angela, Okudo, Charles, Juma, Dennis, Yeda, Redemptah, Andagalu, Ben, Wanja, Elizabeth, Kamau, Edwin, Schnabel, David, Bulimo, Wallace, Waters, Norman C., Walsh, Douglas S., Johnson, Jacob D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652850/
https://www.ncbi.nlm.nih.gov/pubmed/23675533
http://dx.doi.org/10.1371/journal.pone.0064299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652850/
https://www.ncbi.nlm.nih.gov/pubmed/23675533
http://dx.doi.org/10.1371/journal.pone.0064299

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