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Mice Lacking Pten in Osteoblasts Have Improved Intramembranous and Late Endochondral Fracture Healing

The failure of an osseous fracture to heal (development of a non-union) is a common and debilitating clinical problem. Mice lacking the tumor suppressor Pten in osteoblasts have dramatic and progressive increases in bone volume and density throughout life. Since fracture healing is a recapitulation...

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Detalles Bibliográficos
Autores principales: Burgers, Travis A., Hoffmann, Martin F., Collins, Caitlyn J., Zahatnansky, Juraj, Alvarado, Martin A., Morris, Michael R., Sietsema, Debra L., Mason, James J., Jones, Clifford B., Ploeg, Heidi L., Williams, Bart O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652860/
https://www.ncbi.nlm.nih.gov/pubmed/23675511
http://dx.doi.org/10.1371/journal.pone.0063857