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Mice Lacking Pten in Osteoblasts Have Improved Intramembranous and Late Endochondral Fracture Healing
The failure of an osseous fracture to heal (development of a non-union) is a common and debilitating clinical problem. Mice lacking the tumor suppressor Pten in osteoblasts have dramatic and progressive increases in bone volume and density throughout life. Since fracture healing is a recapitulation...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652860/ https://www.ncbi.nlm.nih.gov/pubmed/23675511 http://dx.doi.org/10.1371/journal.pone.0063857 |