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Mice Lacking Pten in Osteoblasts Have Improved Intramembranous and Late Endochondral Fracture Healing
The failure of an osseous fracture to heal (development of a non-union) is a common and debilitating clinical problem. Mice lacking the tumor suppressor Pten in osteoblasts have dramatic and progressive increases in bone volume and density throughout life. Since fracture healing is a recapitulation...
Autores principales: | Burgers, Travis A., Hoffmann, Martin F., Collins, Caitlyn J., Zahatnansky, Juraj, Alvarado, Martin A., Morris, Michael R., Sietsema, Debra L., Mason, James J., Jones, Clifford B., Ploeg, Heidi L., Williams, Bart O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652860/ https://www.ncbi.nlm.nih.gov/pubmed/23675511 http://dx.doi.org/10.1371/journal.pone.0063857 |
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