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A knowledge based approach to matching human neurodegenerative disease and animal models

Neurodegenerative diseases present a wide and complex range of biological and clinical features. Animal models are key to translational research, yet typically only exhibit a subset of disease features rather than being precise replicas of the disease. Consequently, connecting animal to human condit...

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Detalles Bibliográficos
Autores principales: Maynard, Sarah M., Mungall, Christopher J., Lewis, Suzanna E., Imam, Fahim T., Martone, Maryann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653101/
https://www.ncbi.nlm.nih.gov/pubmed/23717278
http://dx.doi.org/10.3389/fninf.2013.00007