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Microtubule Alterations Occur Early in Experimental Parkinsonism and The Microtubule Stabilizer Epothilone D Is Neuroprotective

The role of microtubule (MT) dysfunction in Parkinson's disease is emerging. It is still unknown whether it is a cause or a consequence of neurodegeneration. Our objective was to assess whether alterations of MT stability precede or follow axonal transport impairment and neurite degeneration in...

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Detalles Bibliográficos
Autores principales: Cartelli, Daniele, Casagrande, Francesca, Busceti, Carla Letizia, Bucci, Domenico, Molinaro, Gemma, Traficante, Anna, Passarella, Daniele, Giavini, Erminio, Pezzoli, Gianni, Battaglia, Giuseppe, Cappelletti, Graziella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653217/
https://www.ncbi.nlm.nih.gov/pubmed/23670541
http://dx.doi.org/10.1038/srep01837