Effect of the APOE Polymorphism and Age Trajectories of Physiological Variables on Mortality: Application of Genetic Stochastic Process Model of Aging

We evaluated effects of the APOE polymorphism (carriers versus noncarriers of the e4 allele) and age trajectories of total cholesterol (CH) and diastolic blood pressure (DBP) on mortality risk in the Framingham Heart Study (original cohort). We found that long-lived carriers and noncarriers have dif...

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Detalles Bibliográficos
Autores principales: Arbeev, Konstantin G., Ukraintseva, Svetlana V., Kulminski, Alexander M., Akushevich, Igor, Arbeeva, Liubov S., Culminskaya, Irina V., Wu, Deqing, Yashin, Anatoliy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653307/
https://www.ncbi.nlm.nih.gov/pubmed/23682334
http://dx.doi.org/10.6064/2012/568628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653307/
https://www.ncbi.nlm.nih.gov/pubmed/23682334
http://dx.doi.org/10.6064/2012/568628

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