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The asymmetric segregation of damaged proteins is stem cell–type dependent

Asymmetric segregation of damaged proteins (DPs) during mitosis has been linked in yeast and bacteria to the protection of one cell from aging. Recent evidence suggests that stem cells may use a similar mechanism; however, to date there is no in vivo evidence demonstrating this effect in healthy adu...

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Detalles Bibliográficos
Autores principales: Bufalino, Mary Rose, DeVeale, Brian, van der Kooy, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653353/
https://www.ncbi.nlm.nih.gov/pubmed/23649805
http://dx.doi.org/10.1083/jcb.201207052