Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function in Drosophila

During autophagy, phagophores capture portions of cytoplasm and form double-membrane autophagosomes to deliver cargo for lysosomal degradation. How autophagosomes gain competence to fuse with late endosomes and lysosomes is not known. In this paper, we show that Syntaxin17 is recruited to the outer...

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Detalles Bibliográficos
Autores principales: Takáts, Szabolcs, Nagy, Péter, Varga, Ágnes, Pircs, Karolina, Kárpáti, Manuéla, Varga, Kata, Kovács, Attila L., Hegedűs, Krisztina, Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653357/
https://www.ncbi.nlm.nih.gov/pubmed/23671310
http://dx.doi.org/10.1083/jcb.201211160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653357/
https://www.ncbi.nlm.nih.gov/pubmed/23671310
http://dx.doi.org/10.1083/jcb.201211160

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