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Behavioral characterization of the 6-hydroxidopamine model of Parkinson’s disease and pharmacological rescuing of non-motor deficits

BACKGROUND: Parkinson’s disease (PD) is a chronic neurodegenerative condition that is characterized by motor symptoms as a result of dopaminergic degeneration, particularly in the mesostriatal pathway. However, in recent years, a greater number of clinical studies have focused on the emergence of no...

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Detalles Bibliográficos
Autores principales: Carvalho, Miguel M, Campos, Filipa L, Coimbra, Bárbara, Pêgo, José M, Rodrigues, Carla, Lima, Rui, Rodrigues, Ana J, Sousa, Nuno, Salgado, António J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653696/
https://www.ncbi.nlm.nih.gov/pubmed/23621954
http://dx.doi.org/10.1186/1750-1326-8-14