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The combination of ANT2 shRNA and hNIS radioiodine gene therapy increases CTL cytotoxic activity through the phenotypic modulation of cancer cells: combination treatment with ANT2 shRNA and I-131

BACKGROUND: It is important to simultaneously induce strong cell death and antitumor immunity in cancer patients for successful cancer treatment. Here, we investigated the cytotoxic and phenotypic modulation effects of the combination of ANT2 shRNA and human sodium iodide symporter (hNIS) radioiodin...

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Detalles Bibliográficos
Autores principales: Choi, Yun, Lee, Ho Won, Lee, Jaetae, Jeon, Yong Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653759/
https://www.ncbi.nlm.nih.gov/pubmed/23522027
http://dx.doi.org/10.1186/1471-2407-13-143