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Alternative CHRNB4 3′-UTRs Mediate the Allelic Effects of SNP rs1948 on Gene Expression

Common genetic factors strongly contribute to both nicotine, the main addictive component of tobacco, and alcohol use. Several lines of evidence suggest nicotinic acetylcholine receptors as common sites of action for nicotine and alcohol. Specifically, rs1948, a single-nucleotide polymorphism (SNP)...

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Detalles Bibliográficos
Autores principales: Gallego, Xavier, Cox, Ryan J., Laughlin, James R., Stitzel, Jerry A., Ehringer, Marissa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653846/
https://www.ncbi.nlm.nih.gov/pubmed/23691088
http://dx.doi.org/10.1371/journal.pone.0063699