Role of SUMO-Specific Protease 2 in Reprogramming Cellular Glucose Metabolism

Most cancer cells exhibit a shift in glucose metabolic strategy, displaying increased glycolysis even with adequate oxygen supply. SUMO-specific proteases (SENPs) de-SUMOylate substrates including HIF1α and p53,two key regulators in cancer glucose metabolism, to regulate their activity, stability an...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Shuang, Huang, Gang, Tong, Xuemei, Xu, Lian, Cai, Rong, Li, Jie, Zhou, Xiang, Song, Shaoli, Huang, Chen, Cheng, Jinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653847/
https://www.ncbi.nlm.nih.gov/pubmed/23691130
http://dx.doi.org/10.1371/journal.pone.0063965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653847/
https://www.ncbi.nlm.nih.gov/pubmed/23691130
http://dx.doi.org/10.1371/journal.pone.0063965

Ejemplares similares