The C-Terminus of Human Nucleotide Receptor P2X7 Is Critical for Receptor Oligomerization and N-Linked Glycosylation

BACKGROUND: The P2X(7) receptor binds extracellular ATP to mediate numerous inflammatory responses and is considered a potential biomarker and therapeutic target for diverse inflammatory and neurological diseases. P2X(7) contains many single nucleotide polymorphisms, including several mutations loca...

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Detalles Bibliográficos
Autores principales: Wickert, Lisa E., Blanchette, Joshua B., Waldschmidt, Noelle V., Bertics, Paul J., Denu, John M., Denlinger, Loren C., Lenertz, Lisa Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653848/
https://www.ncbi.nlm.nih.gov/pubmed/23691096
http://dx.doi.org/10.1371/journal.pone.0063789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653848/
https://www.ncbi.nlm.nih.gov/pubmed/23691096
http://dx.doi.org/10.1371/journal.pone.0063789

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