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Maternal Low-Protein Diet Affects Epigenetic Regulation of Hepatic Mitochondrial DNA Transcription in a Sex-Specific Manner in Newborn Piglets Associated with GR Binding to Its Promoter

Mitochondrial oxidative phosphorylation (OXPHOS) plays an important role in energy homeostasis by controlling electron transfer and ATP generation. Maternal malnutrition during pregnancy affects mitochondrial (mt) DNA-encoded OXPHOS activity in offspring, yet it is unknown whether epigenetic mechani...

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Detalles Bibliográficos
Autores principales: Jia, Yimin, Li, Runsheng, Cong, Rihua, Yang, Xiaojing, Sun, Qinwei, Parvizi, Nahid, Zhao, Ruqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653849/
https://www.ncbi.nlm.nih.gov/pubmed/23691106
http://dx.doi.org/10.1371/journal.pone.0063855