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Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

Pancreatic neuroendocrine tumors (PanNETs) are a relatively rare but clinically challenging tumor type. In particular, high grade, poorly-differentiated PanNETs have the worst patient prognosis, and the underlying mechanisms of disease are poorly understood. In this study we have identified and char...

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Detalles Bibliográficos
Autores principales: Hunter, Karen E., Quick, Marsha L., Sadanandam, Anguraj, Hanahan, Douglas, Joyce, Johanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653861/
https://www.ncbi.nlm.nih.gov/pubmed/23691228
http://dx.doi.org/10.1371/journal.pone.0064472